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37 Current studies further demonstrated that HIF-1 inhibited two enzymes in FAO, the medium- and long-chain acyl-CoA dehydrogenases MCAD and LCAD
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However, rather than directly affecting FAO, SCAP deficiency suppressed regulation of genes involved in sterol biosynthesis, including critical enzymes such as 3-hydroxy-3-methylglutaryl coenzyme A reductase
Alterations in mitochondrial DNA copy number and the activities of electron transport chain complexes and pyruvate dehydrogenase in the frontal cortex from subjects with autism
