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Description
[141] Although there have been sporadic synthetic efforts since 1972, [140] the EschenmoserWoodward synthesis remains the only completed (formal) total synthesis
10.1002/iub.1409 64 MartoN.MorelloJ.AntunesA
Zatsepina O, Karpov D, Chuvakova L et al (2020) Genome-wide transcriptional effects of deletions of sulphur metabolism genes in Drosophila melanogaster
In response to various PAMPs and DAMPs, NLRP3 oligomerizes with the adapter protein ASC to form a high molecular weight complex that recruits and cleaves pro-caspase-1, activating it and driving the maturation of IL-1 and IL-18, GSDMD cleavage, and pyroptosis
