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(51) analyzed 59 formalin-fixed paraffin-embedded (FFPE) samples of medullary thyroid carcinoma (MTC) with and without stromal desmoplasia

Each plasmid in the pool co-expresses a unique sgRNA, targeting a distinct site within the Gpx4 locus, alongside the Streptococcus pyogenes Cas9 nuclease, and encodes GFP to enable fluorescent identification and enrichment of successfully transfected cells

References Lemont H, Ammirati KM, Usen N
