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The ISR-dependent gene Trib3 was notably upregulated in the liver of cysteine-deprived animals

Thats exactly why so many in-vitro experiments use fibroblast cultures as their starting point when studying this compound

42 Huang YY, Huang XF, Tang HQ, Wang JN Learning and memory abilities in mice with Alzheimer's disease after pre-intragastric infusion of Centella asiatica water decoction

Journal of Orthopaedic Research, 21 (5), 976983