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Some protocols recommend using higher concentrations (3% to 4%) specifically in these deep creases while using moderate concentrations elsewhere

Transition metals with two contiguous oxidation states, typically Fe and Cu, but also Co and Ni, are able to catalytically convert endogenous, naturally produced hydrogen peroxide into the hydroxyl radical through radical-chain mechanisms such as that long known as the Fenton reaction [12] (Scheme 2)

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