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However, because exogenous glucagon relies on existing biochemical reserves to produce an immediate glycemic response, its efficacy is severely blunted in states of prolonged endurance exercise
Li Z, Razavi P, Li Q, Toy W, Liu B, Ping C, et al
Although AKR1B1 can play a protective role by detoxifying acrolein or HNE, it can also play a positive/amplifying role in inflammation through various mechanisms (Figure 2)
Nanosystems in nose-to-brain drug delivery: a review of non-clinical brain targeting studies
