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The study also revealed that AS-IV could alleviate iron-dependent cell death in cardiomyocytes by activating the Nrf2 signaling pathway and enhancing the expression of GPx4, thereby attenuating oxidative stress induced by DOX (Luo et al., 2021a)

Furthermore, they noted that the GST isoform GST-Mu was significantly decreased in patients with MDD, and may be a potential therapeutic target [22]

10.1152/japplphysiol.00359.2003 J

For instance, a panel of four metabolites can distinguish between aqueous humor samples from glaucoma patients, type 2 diabetes patients, and healthy controls with 95% accuracy using a linear model
