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89 In individuals with type 2 diabetes, doses of either 250 or 500 mg of an amla extract standardized to 60% low molecular weight hydrolyzable tannins, taken twice daily, significantly lowered total cholesterol, LDL and VLDL cholesterol, triglycerides, and significantly raised HDL cholesterol levels compared to both baseline and placebo

Moreover, microglial cells (MGCs), a primary source of GLP-1 secretion in the brain, have been implicated in early neurodegeneration in diabetic mouse models (144), highlighting the GLP-1-mediated impact on cognitive function

Hydration: Sip water throughout the day rather than gulping large amounts during meals, which can dilute digestive enzymes and increase stomach volume

Subjects were enrolled in SARP or IMSA studies between February 2013 and January 2019, as previously described (39)