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Vitamin C and Infection A major symptom of the vitamin C deficiency disease scurvy is the marked susceptibility to infections, particularly of the respiratory tract, with pneumonia being one of the most frequent complications of scurvy and a major cause of death [7]

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A survival rate of 23% is generally considered optimal for generating a diverse pool of stable mutants (Shibai et al., 2017

The steady-state concentration of O 2 is about 510 times higher in the mitochondrial matrix than in the cytoplasm or nucleus [39], but the mitochondrial matrix contains Mn-superoxide dismutase (SOD), which can react with O 2 to form hydrogen peroxide (H 2 O 2 ) (Figure 2)