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Description
Damage-associated molecular patterns (DAMPs) activate pattern recognition receptors, triggering the substantial release of pro-inflammatory cytokines (including IL-6, TNF-, and IL-1) and CXC chemokines 6

Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimers disease

From the periphery, the immediate defensive response can be the stable gastric pentadecapeptide BPC 157 therapy [1,2,3,4,5,6,7,8,9,10,11,15,27,28,29,30,33], peripherally and centrally

10.1093/toxsci/kfl131 61 EdmondsB
