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Similar content being viewed by others Introduction Pancreatic ductal adenocarcinoma (PDAC) is predicted to become the third primary cause of cancer-related mortality by 2025 due to its insidious onset, early distal metastasis, and dismal prognosis 1,2

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American Journal of Clinical Nutrition 80, 16111617 [DOI] [PubMed] [Google Scholar] James S.J., Melnyk S., Jernigan S., Cleves M.A., Halsted C.H., Wong D.H

Dysfunction of the ETC, such as deficiencies in Complex III or V, leads to fatty acid accumulation and reduced histone acetylation levels, ultimately impeding hepatocyte proliferation [151]