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Abbreviations AKT: Protein kinase B Apaf-1: Apoptotic protease activating factor-1 ATM: Ataxia-telangiectasia mutated Bax: Bcl-2-associated X protein Bcl-2: B-cell lymphoma 2 Chk2: Checkpoint kinase 2 COX-2: Cyclooxygenase-2 CRC: Colorectal cancer CYP: Cytochrome P450 enzymes EMT: Epithelial-mesenchymal transition ETC: Electron transport chain FU: 5-Fluorouracil GPx: Glutathione peroxidase HIF-1: Hypoxia-inducible factor-1 alpha Keap1: Kelch-like ECH-associated protein 1 MAPK: Mitogen-activated protein kinase MDA-MB-231: Breast cancer cell line MDR: Multi-drug resistance miR: MicroRNA MMP: Matrix metalloproteinase Mn-SOD: Manganese superoxide dismutase mPTP: Mitochondrial permeability transition pore MRN: Complex: MRE11-RAD50-NBS1 complex mTOR: Mammalian target of rapamycin NF-B: Nuclear factor kappa B NICD: Notch intracellular domain Nrf2: Nuclear factor erythroid 2-related factor 2 NSCLC: Non-small cell lung cancer PARP: Poly (ADP-Ribose) polymerase PGE2: Prostaglandin E2 PI3K: Phosphoinositide 3-kinase PLGA: Poly (Lactic-Co-Glycolic Acid) Smad: Mothers against decapentaplegic homolog TGF-: Transforming growth factor-beta VEGFR: Vascular endothelial growth factor receptor Wnt: Wingless-related integration site References Siegel RL, Miller KD, Fuchs HE, Jemal A (2021) Cancer statistics

Dafnee Villa-Garca L, Ral Mrquez-Preciado &, Ortiz-Magdaleno M, et al (2021)Antimicrobial effect of gold nanoparticles in the formation of the Staphylococcus aureus biofilm on a polyethylene surface

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