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[5] Importantly, if both B12 and folate deficiencies are present, B12 should be corrected first to avoid potentially worsening neurological symptoms

Refrigeration Unlike some medications that require strict refrigeration, vitamin B12 injections come in different formulations, and their storage requirements vary: Cyanocobalamin Injections: Many cyanocobalamin B12 injections can be stored at room temperature (68F to 77F / 20C to 25C) and should be kept away from direct light