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LPS, a component of Gram-negative bacteria, binds to Toll-like receptor 4 (TLR4), activating NF-B and the NLRP3 inflammasome, leading to the release of IL-1 and TNF- (Page et al., 2022)

[10] Foods found to contain ergothioneine include liver, kidney, black beans, kidney bean, and oat bran, with the highest levels in bolete and oyster mushrooms, especially in Pleurotus citrinopileatus

Despite some reports on the similarities between senescence and eryptosis at the morphological level [67], intracellular Ca 2+ elevation [74], Ca 2+ -driven activation of Gardos channels [70], PS exposure [76], or ROS contribution [71], senescence of erythrocytes cannot be considered an RCD of these cells and should be clearly distinguished from eryptosis
10.1101/gad.1783809 Genes Dev