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Description
Transmembrane E3 ligase RNF183 mediates ER stress-induced apoptosis by degrading Bcl-xL

In order to not rely only on animal studies, it is worth recalling clinical trials

They are often small-scale and poorly controlled for profound confounders like diet and medication, leading to inconsistent and non-reproducible taxonomic findings

Together, regular physical activity and an antioxidant-rich diet synergistically boost Nrf2 signalling, promoting improved metabolic health and reduced inflammation [5]