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But my upper back started to ache two days after the shot and still bothers me on the 5th of Feb

A typical protocol looks like this: Initial loading (for severe deficiency or pernicious anemia): Daily or every-other-day injections for 1 to 2 weeks, then weekly for 4 weeks Maintenance (pernicious anemia, ongoing absorption issues): Monthly injections indefinitely General wellness or dietary deficiency: Once every 1 to 3 months, depending on levels Your provider will check your B12 blood levels and recommend the right schedule for you

One key difference: tirzepatide is a dual GIP/GLP-1 receptor agonist, while semaglutide targets only GLP-1

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