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Miranda-Vizuete, A., Damdimopoulos, A

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Heterogeneity in growth, secretion, and RNA composition can be found between and within zones of colonization, and the quantitative composition of the secretome of the different zones differs (517, 518)

REIMAGINE 2 was a 68-week efficacy and safety trial investigating once-weekly subcutaneous CagriSema (a fixed dose combination of the amylin receptor agonist, cagrilintide, and the GLP-1 receptor agonist, semaglutide) in two different doses (2.4 mg/2.4 mg and 1.0 mg/1.0 mg) compared to two different doses of semaglutide (2.4 mg and 1.0 mg), cagrilintide (2.4 mg), and placebo