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Thus, GSH is crucial for both -cell function and insulin sensitivity, with its depletion representing a significant factor in diabetes pathogenesis
Journal of Laboratory and Clinical Medicine
Their transient knockdown, except CoQ8 and CoQ6 , reduced CoQ 10 levels, but just CoQ7 knockdown could hamper mitochondrial respiration and elevated ubiquinol to ubiquinone ratios and also cause the accumulation of a putative biosynthetic intermediate characterized by reversible redox property, like CoQ 10 (Yen et al., 2016)
