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Drugs of the tetracycline family are representative examples of this phenomenon (Figure 3)
Theodoropoulou A, Koutroubakis IE (2008) Ischemic colitis: clinical practice in diagnosis and treatment
Pregnant or breastfeeding women should consult their physician before use
This in turn leads to redistribution of the lipophilic drug from the target tissues into the blood, lowering drug concentration in the target tissues
