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Motor symptoms such as tremor, stiffness, and slowed movement are the most visible signs of the disease, though nonmotor symptoms are also common

Participants received once-weekly subcutaneous semaglutide (2.4 mg) plus lifestyle counseling, compared to placebo plus lifestyle counseling

[122] observed that no tumor had distant metastases without affecting the sentinel lymph nodes, suggesting less importance of searching for metastases in distant organs when lymph node metastasis is absent
Addressing the root sleep disruption directly can resolve downstream energy and recovery complaints without adding other therapies prematurely
