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Together this investigation revealed that succinicGSH is formed by succination of newly synthesized GSH and that this metabolite is partly degraded into succinated cysgly and partly secreted to the media (See Fig
These findings demonstrate that ROS exert a direct effect in mediating bronchial responsiveness and asthma

Eck HP, Gander H, Hartmann M, et al

[DOI] [PubMed] [Google Scholar] Rauckhorst A.J., Gray L.R., Sheldon R.D., Fu X., Pewa A.D., Feddersen C.R., Dupuy A.J., Gibson-Corley K.N., Cox J.E., Burgess S.C
