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Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis

however, this enzyme may be retarded in Flavin insufficient states due to the fact that the second step in its pathway requires FAD for dimethyl glycine (DMG) HCY de-methylation and without sufficient FAD, DMG accumulates and the BHMT betaine degradation pathway is stalled (87)

Phytochemistry 59 (5), 537542
doi:10.1371/journal.pone.0051189
