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Birsoy and colleagues also found how mitochondrial glutathione drives cancer spread: not by acting as an antioxidantan effect ruled out through multiple experimentsbut by signaling to activate ATF4, a transcription factor that helps cancer cells survive in low-oxygen conditions

Also, further studies should assess whether SASP may be used for the prevention or the treatment of metastatic breast cancer

In fact, Metformin may have a significant impact on longevity, positively impact several hallmarks of aging, and even extend healthspan
