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To achieve this, we employed an iterative registration framework called Elastix (43), complemented by a Python wrapper package named Pyelastix (accessible at The transformation parameters were computed based on the nuclear channel obtained in each cycle, where the initial cycle served as the reference to which all subsequent cycles were aligned

Section 1886(m)(5)(C) of the Act requires LTCHs to submit to the Secretary quality measure data specified under section 1886(m)(5)(D) in a form and manner, and at a time, specified by the Secretary