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Second, altering the microbiome can have unintended effects beyond TMA production so changes should ideally be done under clinical supervision when possible

Regulation of expression of steroidogenic enzymes in Leydig cells
Each variant changes evolutionarily conserved amino acids and is predicted to be deleterious
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However, Lactobacillus and Bifidobacterium , as probiotics, regulate the immune response, showing anti-inflammatory effects and protecting the body from pathogens [34]
