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301,302,303,304,305 Besides controlling the virus replication, PARPs or sirtuins also contributes to the oncogenic virus infection, such as oncogenic gamma herpesviruses KSHV and Epstein Barr virus (EBV) infection, and the tumorigenesis through the epigenetic remodeling

Although NNMT may affect nicotinamide levels and NAD+ pathways, the real impact in the body is still unclear

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