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Many of these species (about 45%) are herbivores by partly or completely feeding on plants and represent a significant proportion of pests or pollinators for economically important crops

MS, IR-B, and PG: writingreview and editing

10.1016/j.teac.2017.05.001 13 KapoorR.WangC

The development of selective delivery systems, including nanoparticle-based carriers or tumor-targeted prodrugs, alongside adaptive clinical trial designs incorporating metabolic biomarkers, will be pivotal in overcoming these hurdles
