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(PubMed) Clark LC, Combs GF, Jr., Turnbull BW, et al
A study on isolated aortas of streptozotocin-nicotinamide diabetic-induced rats demonstrated that quercetin's synergistic effects on the administration of anti-diabetic medications, including metformin, reversed endothelial damage
Selenoprotein P expression is controlled through interaction of the coactivator PGC-1 with FoxO1a and hepatocyte nuclear factor 4 transcription factors

Moreover, CBD prevents the oxidation of glutathione (GSH) and other non-enzymatic antioxidants 19 , and chelates non-protein-bound metal ions involved in the Fenton reaction 22
