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VPA induced hepatotoxicity is a welldocumented undesirable effect and can present clinically in different forms such as an asymptomatic and reversible elevation of aminotransferases (alanine transaminase or aspartate aminotransferase), hyperammonaemia with minimal or no liver injury and acute hepatocellular injury with jaundice which can progress to fulminant liver failure

Core symptoms include widespread musculoskeletal pain lasting at least three months, commonly accompanied by fatigue, sleep disturbance, cognitive issues (fibro fog), mood symptoms, stiffness, and tenderness

A., & Hamid, P

doi: 10.1590/1414-431X20143467