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Cai N, Zhao X, Jing Y, et al

Visceral fat is strongly associated with increased cardiovascular disease risk, and its reduction typically correlates with improved cardiovascular health markers

Combining semaglutide with other peptide pathways, like those targeted by tirzepatide (which activates both GLP-1 and GIP receptors), can activate fresh pathways and bypass this adaptation

doi: 10.1023/A:1026718308155
