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doi: 10.1096/fj.04-3260com 37 MadsenKLLewisSATaverniniMMHibbardJFedorakRN

10.1002/gps.4196 2

1 An alternative mechanism by which medications may enhance APAP hepatotoxicity involves competitive utilization of the glucouronidation pathway, resulting in increased metabolism towards the CYP system and thus enhanced formation of hepatotoxic substrates

[DOI] [PubMed] [Google Scholar] 21.Chen S., Wang X., Cheng Y., Gao H., Chen X
