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Description
It has been reported that lung cancer cells exhibit upregulated expression of all key glycolytic enzymes [hexokinase 2 (HK2), phosphofructokinase and pyruvate kinase (PK)] (13), suggesting that the essential enzymes of the aerobic glycolytic pathway have a critical role in the development of lung carcinoma

Therefore, the metabolic switch meets the higher energy requirements, generates metabolic intermediates required for the biosynthesis of macromolecules, and suppresses the metabolic features of rest lymphocytes

Rather than being direct alternatives, they are often viewed as complementary research tools

[DOI] [PubMed] [Google Scholar] 149.Morales P., Reggio P.H., Jagerovic N
