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Menzies et al., 2020) which may contribute to the elevated oxidative stress, inflammation, and metabolic dysfunction observed in these conditions
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By contrast, LXA4 and lipoxin B4 (LXB4) demonstrated protective effects by suppressing the activation and cytokine release from MS-derived monocytes in vivo, improving BBB integrity, and limiting monocyte migration [265]
doi: 10.3390/ijms252111422
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10.1016/j.expneurol.2020.113519 52 GeislerS.DoanR
