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Lancet Psychiatry 3, 760773

Xenograft mouse models Mice were injected subcutaneously with 1 10 7 stable cells ( n = 6 for each group)

Dysfunctional ER signaling may also alter 5-HT transporter (SERT) activity and increase 5-HT1A receptor binding in the amygdala, enhancing the processing of negative emotions and heightening vulnerability to depression and anxiety (60,61)