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FIGURE 3 6.1 Avascularity and nutrient deficiency The intervertebral disc (IVD) is the largest avascular tissue in the human body, and its cells depend on the diffusion of nutrients from surrounding blood vessels through the cartilage endplate (CEP) into the tissue interior
In the UK, diagnosis of B12 deficiency is primarily made through blood testing
IMPORTANT: If you suspect an abscess, make sure to seek medical care right away

They're much faster than QM- or MD-based methods, typically requiring only a small amount of computational work to predict p K a values for an unseen structure
