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& Lemasters, J
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D1 functions predominantly as a scavenger enzyme that deiodinates sulfated TH while being cleared in the bile and urine (220)
For each peptide, separate GP models for peptide intensities in the absence (control condition) and presence of an osmolyte (osmolyte condition) and a joint model were defined, and model hyperparameters were found by maximizing the sum marginal log likelihood across all models using Adam optimizer with a learning rate of 0.1 and 1,000 iterations
