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HGH binds the GHR on hepatocytes, activating the JAK2/STAT5 signaling cascade and stimulating transcription of the IGF-1 gene, producing 70% of circulating IGF-1

10.1039/c3cc42493f Summary Keywords antioxidants, antioxidant enzymes, improved and reusable peroxidase activity, self-assembly, particles, nanotubes, micelles Citation Carmona-Ribeiro AM, Prieto T and Nantes IL (2015) Nanostructures for peroxidases

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Mice without the ability to produce CuZnSOD showed no apparent abnormalities up until early adulthood but had shorter lifespan and more than 70% of them developed liver cancers later in life