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Thus, the discovery that NAC can also exert its antioxidative effects in a GSH-independent manner warrants re-evaluation of the possible therapeutic use of NAC regarding other pathological conditions unrelated to disturbances in GSH levels
However, these lesions can also be induced in both rats and mice after viral infection (Bergs and Scotti 1967) or exposure to certain drugs or chemicals (Mendenhall and Chedid 1980
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