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[DOI] [PubMed] [Google Scholar] 55.Friesen C, Kiess Y, Debatin KM

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Introduction A high blood level of Homocysteine (HCys) has been regarded, in the last 10 years, as a biomarker of cardiovascular disease as well as a risk factor for many other pathologies, including Alzheimer's and other dementias ( Homocysteine (HCys) is a non-essential amino acid that derives from the biosynthesis and metabolism of methionine (Met)

Glutathione depletion in mitochondria made them more sensitive to ROS production and subsequent oxidative stress
