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Ji X, Zhang P, Armstrong RN, Gilliland GL

Pegylated arginine arginase (PEG-BCT-100) showed promising tumor suppressive activity, survival advantage, and safety against advanced HCC in phase I clinical trials of combination chemotherapy (oxaliplatin and capecitabine)

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Second, they indicate minimal risk of allergic or hypersensitivity reactions, which can occur when immune responses develop against therapeutic peptides
