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Cisplatin otoprotection using transtympanic L-N-acetylcysteine: a pilot randomized study in head and neck cancer patients

Further, an LPS administration model of systemic inflammation in sepsis in conjunction with convulsant PTZ treatment in mice increased seizure susceptibility, which was attenuated with NOX2 genetic ablation and inhibition (Huang et al., 2018)

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These data indicate that NAC treatment can scavenge ROS indirectly enhance the integrin 51 and PI3K/AKT signaling pathways to promote the tenogenic differentiation of TSPCs