glutathione comes from A Review of Dietary (Phyto)Nutrients for Support Glutathione Synthase - an overview
Description
Later, the hepatic nuclear localization of GSH was also documented: high concentrations of this tripeptide have been found in the nucleus of intact hepatocytes and a nuclear/cytoplasmic concentration gradient was maintained by active mechanisms [51]

Astaxanthin is another powerful xanthophyll carotenoid antioxidant thats been extensively studied for its role in skin health because of its powerful photo-protective, antioxidant, and anti-inflammatory properties
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Lightening skin in patches Glutathione can make skin lighter in spots if it isnt watched well, especially in persons with skin types that have a lot of melanin

A similar scenario has in fact been reported recently in an alcoholic liver disease model in which long-term alcohol consumption activated NF-B in Kupffer cells, whereas NF-B activation in hepatocytes was inhibited 45
