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which can act both in the intracellular and extracellular space [14,19]
Furthermore, these nanocarriers are capable of depleting GSH levels in the tumor microenvironment to augment stress on cells and induce cell death pathways, including ferroptosis, making cancer cells sensitive to treatment Fig
It contributes to increased levels within the body itself
Moreover, andrographolide can induce apoptosis in fibroblast-like synoviocytes by increasing mitochondrial cytochrome release and promoting the activation of caspase-3 ( 5.3 Gout Inhibiting inflammation is crucial in the treatment of gout
