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Patients with GATM deficiencies have milder clinical manifestations which are generally limited to moderate intellectual disability and language disorder

Talukdar J, Bhadra B, Dattaroy T, Nagle V, Dasgupta S

While 12 weeks of bright light exposure did not produce measurable improvements in sleep quality, glucose metabolism, or inflammatory markers, it significantly altered clock gene expression in peripheral blood mononuclear cells (PBMCs, specifically decreasing REV-ERB levels and increasing the REV-ERB/BMAL1 ratio)

The tentative finding was that the phosphorylation levels of FAK and paxillin appeared to increase in the presence of BPC-157