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A phase 1 clinical trial in RTT patients found no adverse effects of recombinant human IGF-1 (rhIGF-1) (Khwaja et al

Effect of acetyl-L-carnitine on forebrain cholinergic neurons of developing rats Int J Dev Neurosci 1991

[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Rudroff T., et al

Already in the 1940s, Charles Huggins and his colleagues demonstrated the effectiveness of ADT through surgical castration, which removes the major source of systemic androgen synthesis, as a treatment for advanced metastatic CaP [5, 6]
