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(10) Under discussion are circadian rhythms of CYP and DILI, as well as SIRTUIN1 (SIRT1) influencing injury

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4, 5 To extend these observations to cisplatin treatment, the cell sensitivity was evaluated in glioma cell lines with different p53 status: U87MG and U343MG (p53wt) and U251MG and U138MG (p53mt)