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Here, Paul Yen and colleagues describe and summarize the key features of direct thyroid hormone regulation of lipogenesis, fatty acid -oxidation, cholesterol synthesis and the reverse cholesterol transport pathway in normal and altered thyroid states.

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In vitro experiments with SH-SY5Y neuronal cells demonstrated that palmitoyl-L-carnitine treatment enhanced tau phosphorylation, increased mitochondrial fission, and elevated intracellular calcium levels

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