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Astrocytes initiate inflammation in the injured mouse spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor/MyD88-dependent fashion

Further, the study was also designed to test the homocysteine theory of depression, ie, circumventing the patients genetic inability to metabolize B vitamins by administering the metabolized forms in an optimal preparation for CNS availability would lower homocysteine, increase monoamine production, and facilitate clinical improvement

Haack M, Hinze-Selch D, Fenzel T, Kraus T, Kuhn M, Schuld A et al (1999)

Main text Vitamins Vitamin A and Carotenoids Vitamin A is a group of animal-derived fat-soluble retinoids essential for cell growth, cell differentiation, immunity, and vision