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PLC-1a is mainly located in the cytoplasm, while PLC-1b is mainly located in the nucleus of the cells
Future research should focus on targeted, multidisciplinary interventions that address both hepatic and endocrine dysfunction concurrently, paving the way for more personalized and effective therapeutic strategies
The ideal trial duration clearly depends on the expected mechanism of the treatment to be studied and relies heavily on the primary outcome measure chosen

doi: 10.1111/bpa.12071