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Description
Despite promising preclinical outcomes, their clinical translation is hindered by poor solubility, instability, and batch variability
For solubilizing these polypeptides, variables such as non-denaturing detergents (IGEPAL CA-630), changing the ionic strength of the cell lysis and solubilization buffer, addition of BugBuster, diluting the cell lysate and sonication were introduced
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the difference in mean LBM between the groups was 2.92 % (95% CI 1.284.61
